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Among participants who met criteria for metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) at baseline, more than 80% in the 8mg and 12mg cohorts no longer met those criteria after treatment effectively resolving their fatty liver disease
0.24%, respectively
However, it was less effective in the suppression of nitrotyrosine formation
Starting doses are generally cheaper ($149-249/month) while maintenance doses at 1.7 mg or 2.4 mg can cost $199-499/month
A faster onset of any GLP-1 side effects like nausea
If successful, the strategy could support longer-lasting islet cell replacement and move the therapy closer to becoming a functional treatment for people with type 1 diabetes
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